3D Spatial Multi-Omics: The Next Dimension of Tissue Biology
Conventional spatial biology methods rely on thin, 5–10 μm tissue sections. But even following computational reconstruction these thin tissue slices strip away the true three-dimensional context of cell-cell interactions. 3D spatial multi-omics takes a different approach: rather than reconstructing thin tissue images into a “2.5D” approximation of the whole, it captures gene expression, RNA translation, […]