Become a 3D pioneer with early access

Be among the first to explore spatial biology’s next dimension with Pyxa 3D technology access services

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Sample-to-answer in-situ, 3D, single cell spatial analysis

Access the power of the Pyxa platform – the only technology that provides high-plex multiomics data from individual cells in thick tissue sections – with our end-to-end services.

Getting started is easy. Send Stellaromics your sample, and we’ll handle the rest. Our process consists of:

  1. Tissue sectioning at 20-100µm
  2. Full sample preparation with target probe set
  3. In situ 3D sequencing on cleared tissue
  4. Data analysis and report generation

Click below to see our sample inputs and data outputs generated by our data analysis systems.

Inputs
  • You provide an embedded tissue block. We handle the rest from sample to answer!
  • Gene panel customization is available.
Outputs
  • Cell by gene matrix including XYZ locations and subcellular localization.
  • 3D cell mosaic and cell segmentation TIFF images.
  • Customized data and QC reports.
  • Guidance on open-source visualization and analysis tools.
View Detailed Workflow

Three-dimensional data drives actionable insights

Request a Sample Report

Leverage our pre-validated mouse brain 3D pan-neural
cell typing panel for faster results

For neuroscience applications, our ready-to-use 250 Gene Mouse Brain Panel provides ample transcriptional coverage, regardless of the brain region, with an emphasis on genes that are functionally relevant for inflammation, recent neuronal activity, and more, including:

  • Major neurotransmitter genes of interest: Slc17a6/7/8, Slc32a1, Gad1, Gad2, Th, Ddc, Slc6a3, Slc18a2, Chat, Tph2, and many neuropeptides.
  • Inclusion of canonical markers neuroscientists rely on: cortical interneuron markers, steroid hormone receptors (Esr1, Ar, Pgr), Drd1/Drd2, other neuropeptides and receptors.
  • Inclusion of general markers relevant for most experiments: activation of astrocytes and microglia (Gfap, Aldoc, Cd68, Cd45), IEGs (Fos, Egr1), cell division (Top2a).

Full gene list available by request.

Pioneer 3D analysis of new tissue types

Not working on a neuroscience project? Let us know about your needs and we can explore full sample preparation with a customizable set of target probes.

Other tissues we have worked with include:

  • Kidney
  • Patient Biopsies
  • Retina
  • Spleen
  • Tumor

Stay ahead of the curve.

Contact us to learn more about running a services project with Stellaromics.